Cinference is a Berlin and Göttingen-based startup that is revolutionizing the field of protein therapy design. Instead of relying on costly and time-consuming experimental processes, Cinference utilizes innovative computational methods to design de novo protein therapies. Their goal is to create the perfect protein therapeutics that are tailored to specific diseases, eliminating the need for trial and error.

At Cinference, the future of protein design is their priority. They employ a combination of biology, chemistry, and mathematics to tackle the computational problem of protein design. Using machine learning-based computational tools, they can develop proteins with the ideal properties for effective and safe medicine.

Their design process incorporates proprietary data generated in their state-of-the-art laboratory, as well as publicly stored data, ensuring swift and accurate protein design. Cinference's design engine focuses on three key aspects. They use machine learning to design the backbone of the protein candidate, fine-tune the functional site for improved binding interaction, and employ energy scores and simulations for in-silico evaluation.

In their laboratory, they thoroughly validate their proteins, generating training data to ensure excellent biophysical properties. One of the many advantages of Cinference's designed small therapeutic proteins is their high degree of precision in design and functions. They exhibit high stability and solubility, allowing for large-scale production in cost-effective microbial systems or cell-free systems.

Additionally, these proteins can be produced more quickly and in higher yields than antibodies and recombinant proteins, without the need for post-translational modifications. Moreover, they offer higher freedom to operate within the patent landscape. For those interested in protein design and discovery, Cinference offers partnering opportunities.

Their platform is designed to enable others to leverage their expertise in protein design and improve disease treatments. To get in touch with Cinference, simply fill out their contact form on their website. Cinference is comprised of a highly driven and interdisciplinary team that possesses the vision to cure previously untreatable diseases and make gene therapies accessible to all.

With a blend of expertise in biology, data science, machine learning, and more, they are committed to pushing the boundaries of innovation in the field of protein therapy. Led by co-founders Christian Wirsching and Tu Cuong To, along with a team of world-class scientists and advisors, Cinference is at the forefront of revolutionizing the future of therapies. In conclusion, Cinference is a cutting-edge startup that uses computational methods to design de novo protein therapies.

They aim to create the perfect protein therapeutics by leveraging their expertise in biology, chemistry, mathematics, and machine learning. With a focus on precision, stability, and high yields, their small therapeutic proteins offer a cost-effective alternative to traditional treatments. By partnering with Cinference, others can benefit from their platform and contribute to the advancement of protein design and discovery.

Join Cinference in their mission to build a healthier world through groundbreaking protein innovation. Get in touch with them today to learn more