Greater Cities Commission is the driving force behind Australia's first global city region, known as the Six Cities Region in NSW. As a statutory body reporting directly to the NSW Government, they are responsible for coordinating and aligning the planning that will shape the future of the region. Their goal is to accelerate the delivery of key innovation districts and lead discussions on major city-shaping issues.

The Commission aims to create good jobs closer to where people live, attract world-class industry and talent, and make the cities more productive, livable, and sustainable for everyone. They work to transform the region into a globally leading multi-city region, offering a step change in quality of life and opportunities for all residents. The Six Cities Region comprises the Lower Hunter and Greater Newcastle City, Central Coast City, Illawarra-Shoalhaven City, Western Parkland City, Central River City, and Eastern Harbour City.

By collaboratively building the scale, scope, and potential for better jobs, housing, education, health, environment, and lifestyle opportunities, the Greater Cities Commission is positioning the Six Cities Region as one of the world's great places to live and work