@koutiftherapeutics.com
Koutif Therapeutics is advancing discoveries from researchers at the University of Pittsburgh.
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Description
Koutif Therapeutics is a groundbreaking brand in the field of fighting inflammatory diseases. Their mission is to develop therapeutic compounds that uniquely inhibit the inflammatory cascade. They have developed a medicinal chemistry strategy based on discoveries made by Rama Mallampalli, MD, and Beibei Chen, PhD on inhibitors of the ubiquitin degradation pathway.
This pathway is crucial in modulating inflammation, and inhibiting key proteins involved in the activation cascade can help in the treatment of various diseases. One of their major breakthroughs is the identification of a specific inhibitor, Fbxo3, that allows for the degradation of several potent, pro-inflammatory proteins. This includes proteins involved in adaptive and innate immune signaling pathways.
This novel mechanism has the potential to treat numerous inflammatory conditions, and Fbxo3 has never been targeted before. Koutif Therapeutics' technology is based on intellectual property exclusively licensed from the University of Pittsburgh and the United States Department of Veterans Affairs. They are open to partnering with other organizations to further their research and development efforts.
Contact them today to explore potential collaborations
Company Size
2-10
Year Founded
2017
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