# LSP alignment - **Website:** - **Primary alias:** `lspalignment.com` ## Description LSP Consulting specializes in computational biophysics, focusing on protein dynamics, conformational entropy, and allostery. Its work addresses a challenge in structural biology: proteins with similar structures can behave differently, while conventional structural models may not reveal why. The company’s LSP-MD approach analyzes molecular dynamics simulations to make sidechain motion and the relationships between residue movements visible. Rather than treating residues in isolation, it uses a graph-based method that represents pairwise sidechain behavior and coupling, helping researchers examine how protein dynamics change across conditions. LSP Consulting applies this analysis to questions involving binding selectivity, allosteric signaling, mutations, and functional differences between structurally similar proteins. Its methods include graph-based evaluation of conformational entropy, time-resolved community analysis, and approaches to separating meaningful signals from persistent simulation noise. The resulting analyses are intended to help interpret molecular dynamics data when standard structural comparisons provide little explanation. The website also presents scientific background and publications related to the methods, including examples connecting network changes with protein behavior. ## Industries - 🧪 Science and Education - 🧪 Biology _(under Science and Education)_ ## Logos & icons - logo _(primary)_ — PNG — [download](https://cdn.brandfetch.io/idfV25tFga/w/800/h/800/theme/dark/logo.png?c=1bxid64Mup7aczewSAYMX&t=1793216359557) ## Colors | Name | Hex | Theme | | --- | --- | --- | | Chathams Blue | #1a4f8a | accent | | Cinder | #0f1117 | dark | | Spring Wood | #f7f5f0 | light | ## Fonts - DM Serif Display — asset _(google)_ - DM Sans — asset _(google)_ --- _Source: _ _See [/llms.txt](/llms.txt) for a full list of agent-readable pages, and [/auth.md](/auth.md) for how agents authenticate._