Nucleome is a groundbreaking brand dedicated to discovering precision medicines that benefit patients by harnessing the power of 3D genomics. With a mission to shine a light on the dark genome and cure diseases, Nucleome focuses on the non-coding regions of DNA, which make up around 98% of our genetic material. It is now known that 90% of disease-associated genetic variations originate from these dark regions.

Rather than coding for proteins, the dark genome plays a regulatory role, controlling gene expression and determining the timing and levels of gene activation. This regulatory mechanism is crucial for translating our genetic code into the various cell types that exist. Nucleome recognizes that dysregulation of this mechanism is a known cause of diseases.

By unlocking the potential of the dark genome and decoding which genetic variants regulate which genes in specific cell types, Nucleome aims to revolutionize drug discovery and development