Experience downtown Beaufort's best waterfront dining at Panini's on the Waterfront! Our brand has been a local favorite for 20 years, offering a delightful blend of old-world Italian charm and modern-world cuisine. Situated in the historic Beaufort Bank building, our restaurant provides a picturesque setting for your dining experience. Indulge in our unique and crispy stone-baked pizza, flavorful panini sandwiches, hoagies, large salads, inventive pasta dishes, and fresh local seafood with a Mediterranean flare.

Don't forget to save room for our famous homemade Italian desserts! With both indoor and outdoor seating options, including our scenic river deck, you can enjoy stunning views of Beaufort's Waterfront Park while savoring your meal. Whether it's a romantic night out, a family gathering, or a casual dinner with friends, Panini's on the Waterfront offers something for everyone. Visit us in historic downtown Beaufort, SC, and experience the difference of our new world cuisine with old world Italian charm.

Make a reservation or place an order online for dine-in or carry-out