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Our in situ chemistry & transcriptomics technology generates subcellular gene expression maps with high sensitivity & specificity.
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10x Genomics is a cutting-edge brand that offers revolutionary in situ chemistry and transcriptomics technology. With their highly sensitive and specific approach, they generate subcellular gene expression maps with unprecedented accuracy. At the core of their technology is the use of padlock probe rolling circle amplification chemistry, making them the only commercial in situ platform to utilize this powerful approach.
This enables high sensitivity across a wide range of expression levels, including low expressing and highly degraded transcripts. Additionally, it allows for tunable sensitivity and the ability to distinguish between transcripts with high homology, such as isoforms. The four-step authentication process in their workflow ensures optimal performance, guaranteeing that only true target recognition events are amplified, while suppressing off-target events.
Once the off-instrument chemistry workflow is complete, the Xenium Analyzer is used for transcript detection. An optical signature specific to each gene is generated, resulting in a spatial map of the transcripts across the entire tissue section. 10x Genomics also provides a comprehensive platform that includes the Xenium In Situ Analyzer, a user-friendly interface with fast run times and on-instrument analysis.
They offer a diverse menu of curated panels that can be customized to fit specific research needs. Data visualization is made easy with the Xenium Explorer, providing off-instrument interactive visualization and simplified data quality control. With a dedicated team of spatial experts, 10x Genomics offers exceptional support and guidance throughout the research process.
Visit their website to learn more about their products, request pricing, and explore their resources. Trust 10x Genomics to unlock the power of in situ transcriptomics and revolutionize your research
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