Single Technologies is a pioneering brand that specializes in 3-D Sequencing™, a unique technology that revolutionizes DNA sequencing. With this cutting-edge technology, Single Technologies has the capability to read DNA in volumes, increasing the number of DNA sequences that can be read simultaneously. This innovative approach combines Next Generation Sequencing with Spatial Biology, opening up new possibilities in the field.

By leveraging 3-D Sequencing™, Single Technologies aims to address the need for increased DNA sequencing bandwidth. This has significant implications for identifying and diagnosing rare genetic diseases quickly and accurately. Approximately 8% of the population is affected by rare diseases, and the majority have a genetic component.

In addition, 3-D Sequencing™ enables the detection of many more probes in parallel, facilitating the search for disease-specific biomarkers. Single Technologies also explores the frontiers of cell mapping and organ architecture. By utilizing spatial sequencing, they unlock a detailed understanding of individual cells and the distribution of different cell types within tissues.

This knowledge is crucial for projects like the Human Cell Atlas, which aims to create comprehensive reference maps of all human cell types. At the core of Single Technologies' capabilities is Theta, the world's first 3-D sequencer. Theta pushes the boundaries of sequencing power, allowing large-scale production of DNA data when bandwidth matters.

It can read DNA libraries in solution and cells, as well as perform sequencing in single cells and tissues. With its unique flowcell architecture, Theta facilitates the analysis of multiple unconventional sample types. Single Technologies' vision is to remove the bottleneck in generating sequencing data, empowering scientists to solve complex biological problems with the help of AI.

Their system combines a true confocal scanner, open fluidics technology, and volumetric amplification to achieve unprecedented imaging capabilities, efficient reagent distribution, and parallel reactions in three dimensions. Overall, Single Technologies is paving the way for advanced DNA sequencing, enabling researchers and medical professionals to explore the intricacies of genetics and uncover new insights into human health and biology