Theorem Clinical Research, now known as Acorn AI, is a contract research organization (CRO) headquartered in King of Prussia, Pennsylvania, United States. Founded in 1998, Theorem has been providing comprehensive clinical research and development services to pharmaceutical, biotechnology, and medical device industries. Theorem's headquarters is centrally located in the United States and serves as the main hub for its global operations.

The company operates through various offices and facilities strategically placed across North America, Europe, Australia, and Asia. Notably, Theorem has a strong presence in the United States, with additional offices in Illinois, California, and Maryland. As a CRO, Theorem offers a wide range of products and services to support the entire clinical research process.

These include clinical trial management, data management, statistical analysis, regulatory compliance, and medical writing. The company's expertise covers a broad spectrum of therapeutic areas, such as oncology, neuroscience, cardiology, and infectious diseases. Theorem has established several noteworthy partnerships and collaborations to enhance its global reach and capabilities.

It has formed joint ventures with organizations like Royal Philips, a leading health technology company, and MedAvante-ProPhase, a specialized clinical science organization. These collaborations strengthen Theorem's position in the market and facilitate the development of innovative solutions in clinical research. In terms of market position, Theorem has evolved into a leading CRO with a notable presence in the global clinical research industry.

While specific sales figures are not publicly available, Theorem has consistently demonstrated growth and customer satisfaction, enabling it to compete effectively with other major CROs such as QuintilesIMS (now IQVIA), PRA Health Sciences, and Covance. In recent years, Theorem underwent significant changes and rebranded as Acorn AI. This transformation reflects the company's shift towards integrating advanced analytics and artificial intelligence capabilities into its service offerings.

Acorn AI combines deep clinical and therapeutic expertise with AI-powered tools to provide valuable insights and accelerate drug development. As of the latest available information, Acorn AI continues to operate as a leading CRO, leveraging its expanded capabilities, global presence, and strategic partnerships to deliver comprehensive clinical research solutions to its clients worldwide