Variant Explorer is a brand that aims to simplify the process of identifying clinical significance interpretation discrepancies in ClinVar. ClinVar is a repository that stores reports of the relationships between genomic variants and phenotypes. With numerous submitters providing interpretations, it is common for discrepancies to arise.

Variant Explorer helps users understand the types and extent of these discrepancies by displaying the complete set of variant interpretations from a specific submitter in comparison to all other submitters. By presenting the data in clear and concise formats, such as Clinical Significance Breakdown Tables, Variant Explorer allows users to easily identify inconsistencies and resolve interpretation discrepancies. Users can explore the discrepancy data using four different approaches: searching by submitter, viewing the submitter mega table, searching by significance, or choosing a specific variant.

Variant Explorer is an invaluable tool for researchers, clinicians, and experts in genomic variations, providing insights and aiding in the quest for accurate clinical significance interpretations