Heartbeat is a natively digital, full-service agency that specializes in healthcare challenger brands. With headquarters in New York and Los Angeles, and a global presence powered by Publicis Health, Heartbeat offers a wide range of products and services to its clients. Heartbeat serves as the Agency of Record (AOR) for various healthcare brands, including XenoPort's Horizant for Restless Leg Syndrome, Corcept Therapeutics' Korlym for Cushing's syndrome, Shionogi's Osphena for Dyspareunia (Painful Sex), Johnson & Johnson's Zyrtec for Allergy, and more.

Their services include campaign creative, TV commercials, display and point-of-care media, website development, and mobile apps. They cater to different therapeutic areas such as neurology, endocrinology, women's health, oncology/vaccine, aesthetics, and more. Heartbeat is known as the agency for challenger brands, offering integrated and comprehensive solutions to help these brands thrive in a competitive market.

They provide brand strategy, audience engagement, medical advisory, creative activation, technical engineering, and performance measurement. They also offer specialized Challenger Services like the Challenger ID workshop and Rival Rumble analysis to identify unique opportunities and challenge the competition. With their expertise and innovative approach, Heartbeat helps healthcare challenger brands stand out and achieve success