Amnesty International Portugal is part of a global movement of more than 10 million people working to defend human rights. The organisation investigates and reports on abuses, raises public awareness, and mobilises people to seek justice and protect individuals and communities at risk. Its work covers issues including detention, armed conflict, freedom, migration, the death penalty, and the rights of human rights defenders.

People can support its campaigns by signing petitions, joining urgent-action networks, becoming members or supporters, making donations, volunteering, and taking part in events. Amnesty International Portugal also offers human rights education, youth activism, certified training, and creative initiatives such as Arts for Amnesty. Its website provides news, annual and thematic reports, information on international human rights standards, and accounts of campaigns and achievements. Current initiatives include efforts to protect people facing persecution, promote access to justice, and respond to crises. The organisation also shares opportunities to work with it and provides a shop for visitors who wish to support its work through purchases.