The Gobernación de Antioquia is a public entity responsible for the administration of departmental affairs, as well as the planning and promotion of economic, political, and social development in the region. They offer a wide range of services and products to cater to the needs of the community. Their secretariats cover various sectors including agriculture and rural development, education, human resources and organizational development, government, finance, infrastructure, women's affairs, environment, mining, citizen participation and social development, technology and communications, tourism, health and social protection, security and justice, among others.

Additionally, they manage decentralized entities such as hospitals, cultural institutes, and educational institutions. The Gobernación de Antioquia aims to provide efficient and effective governance while prioritizing the well-being and progress of its constituents. Through their various departments and agencies, they strive to meet the diverse needs of the population and contribute to the overall development of Antioquia