The Portuguese Association for Lysosomal Diseases (APL) is a nonprofit association dedicated to supporting and informing people affected by lysosomal diseases and their families. Its mission spans moral, social, cultural, administrative, medical, technical and financial support, with the aim of helping individuals participate fully in community life. APL also promotes research into the causes of these conditions and the development of specific therapies.

The association provides educational information about the lysosome, disease classifications, symptoms and treatments. Its resources cover conditions including Gaucher, Fabry, Pompe, Hunter, Hurler/Scheie and Niemann-Pick type C, as well as mucopolysaccharidoses, lipidoses and other lysosomal disorders. APL offers practical guidance for families following a rare-disease diagnosis, including information on medical care, reference centres, support groups and disability documentation.

Patients and families can connect with APL through membership, events, news, articles, personal stories, frequently asked questions and useful links. The association also invites supporters to make donations or designate a portion of their income tax to help families access the care and treatments they need.