Avidity

Avidity LLC is a Colorado-based life science company founded in 1996 that develops, manufactures, and sells molecular affinity tools for research. Its core offering is patented AviTag™ technology, which uses the E. coli biotin ligase BirA to attach a single biotin molecule to a specific 15-amino-acid peptide tag. This targeted approach supports oriented presentation on streptavidin-coated surfaces, helping researchers study molecular binding interactions.

Avidity’s products include in vitro biotinylation enzymes, in vivo biotinylation strains, AviTag vectors, purification and detection tools, biotinylated recombinant proteins, cell lines, and enzymes. The company also offers resources such as protocols, literature, and frequently asked questions to support use of its technologies. AviTag has applications in areas including biosensors, diagnostics, proximity assays, and drug screening. Avidity reports that its technology is used by researchers in more than 30 countries and by eight of the world’s ten largest pharmaceutical companies. The company emphasizes scientific progress and welcomes collaboration with academic and for-profit institutions.