BioSkryb Genomics

BioSkryb Genomics is a genomics company headquartered in Durham, North Carolina, focused on helping researchers examine the molecular profile of individual cells. Its platform uses Primary Template-Directed Amplification (PTA) to generate whole-genome data with high genomic integrity and supports analysis of DNA and RNA from the same cell, with methylation described as forthcoming.

The company’s ResolveDNA products provide whole-genome amplification for single cells or low-input DNA, as well as sequencing-ready workflows for identifying variants, copy-number changes, and loss of heterozygosity. ResolveOME combines whole-genome and full-length transcriptome analysis from the same single cell, enabling researchers to study genetic variation alongside gene expression. BioSkryb also offers BaseJumper software, which converts single-cell multiomic sequencing reads into structured, analysis-ready results for interpretation and sharing.

These tools support research in cancer, neurology, aging, immunology, cell and gene therapy, reproductive genetics, and microbiome science. BioSkryb highlights applications including detecting mutations, tracing rare tumor clones, and assessing gene-editing outcomes. Its listed solutions also include ResolveServices, and the company invites researchers to request product information and pricing.