Certitude offers a blood-based breast cancer screening test designed to provide additional information for women with dense breast tissue or elevated risk. The Certitude Test analyzes protein patterns in a blood sample using machine-learning technology to identify patterns associated with breast cancer, with the aim of detecting disease as early as Stage 0. It is intended for women aged 40 and older, including those with dense breasts, inconclusive mammogram results, a family history of breast cancer, or a need for screening beyond mammography. The test is designed to complement, not replace, mammography.

Patients can discuss the test with their healthcare provider or request it through OpenLoop Health, where a licensed provider reviews eligibility. The process includes requesting the test, completing a blood draw, receiving digital results, and discussing them with a doctor. Certitude reports clinical performance measures, including sensitivity and negative predictive value, while noting that results should be considered in context.