C.S.I. Jayaraj Annapackiam Mission Hospital is a healthcare institution in Palayamkottai, Tirunelveli, Tamil Nadu. Established on 21 December 1993 under the vision of the Bishop of the Tirunelveli Diocese, the hospital was founded to provide medical care to people in the area, including underserved communities. It has grown from a small facility into a hospital offering a broad range of clinical services.

Its specialties include cardiology, general medicine and surgery, obstetrics and gynecology, pediatrics, orthopedics, nephrology, neurology, oncology, pulmonology, urology, dermatology, ENT, anesthesia, and mental health care. The hospital provides women’s, newborn, and pediatric care, as well as round-the-clock emergency treatment for conditions such as injuries, cardiac symptoms, burns, and pregnancy complications. Diagnostic support includes a clinical laboratory operating 24 hours for inpatients, alongside services such as imaging. The hospital also operates a pharmacy focused on affordable medicines and an equipped operating theatre for minor and major procedures. Its doctors, nurses, technicians, and other support staff serve patients from Palayamkottai and nearby communities.