Derium & Wifey is an online Pokémon-focused shop offering trading card products, live breaks, and related merchandise. Its catalog includes Pokémon sealed cases, booster boxes and packs, Elite Trainer Boxes, other card products, and Pokémon toys. Shoppers can browse products in English as well as Japanese, Chinese, and Korean categories, with availability varying by item.

The store also hosts live breaks on Twitch, where purchased packs are opened on stream. For the featured break described on the site, the commons, uncommons, code card, and energy are kept by the shop, while the buyer receives the remaining cards. The site also lists sealed booster packs for customers who prefer to keep products unopened. In addition to shopping, visitors are invited to sell or trade their bulk cards.

Customers can connect with Derium & Wifey through its Twitch and YouTube channels and Discord community. The storefront is powered by Shopify and supports multiple currencies and a range of payment options. Product availability can change, and featured items may be sold out.