Échele Cabeza is a Colombian harm-reduction project of Corporación Acción Técnica Social (ATS), focused on promoting self-care and informed decision-making around legal and illegal psychoactive substances and related behaviours. Its work combines practical services, public education and research to help people better understand risks and pleasure in substance use.

The Substance Analysis Service (SAS) provides physical and chemical analysis of samples, offering users information about their composition. The project also shares psychoactive substance alerts, educational resources and publications, and explores emerging trends through articles and talks. For events, Échele Cabeza offers workshops, lectures and tailored harm-reduction support, including services for smaller gatherings and festivals. Its Recovery Zone provides a safe space for assistance and support when people experience psychological crises at events. Psychological orientation is another part of its support offering. Through Soberanía Psicoactiva, an ATS initiative, the project promotes cannabis self-cultivation as a harm-reduction strategy. Based in Bogotá, Échele Cabeza also works in other Colombian cities and invites public participation through donations and community resources.