OpenEye

OpenEye Scientific, now part of Cadence, develops cloud-based molecular modeling and cheminformatics software to support drug discovery and development. Its tools help research teams explore biological targets, identify promising compounds, and optimize leads by combining artificial intelligence with physics-based methods. The company’s offerings include the Orion Molecular Design Platform, Small Molecule Discovery Suite, Antibody Discovery Suite, and Formulations Suite, as well as ROCS X, Target X, and the Gaussian Module. OpenEye also provides cheminformatics and modeling toolkits, visualization and data management applications, molecule search capabilities, and curated databases.

Its solutions address virtual screening, ligand- and structure-based design, molecular properties calculations, biomolecular modeling, protein and data preparation, quantum chemistry, and pocket detection. OpenEye emphasizes searching large chemical spaces, including commercial compounds and protein binding sites, to help accelerate research workflows. In addition to software, the company offers drug discovery consulting, crystal structure prediction for drug formulation, custom scientific method development, and partnerships. Documentation, webinars, publications, support, and academic licensing are available to help users apply its technology.