Gentiss

Gentiss develops engineered skin models and provides analytical services for animal-free in vitro research. Its models support the testing of cosmetic, pharmaceutical, and chemical products, as well as studies of compound safety and efficacy, disease modelling, and microbiome characterization. The Leiden Epidermal Model, which Gentiss says has led the industry for over 30 years, is used for toxicology and dosage testing. Its Full-Thickness Model supports a range of test modalities, while the Fibroblast-Derived Matrix Model combines a stratified epidermis with a xeno-free dermal matrix made exclusively by primary dermal fibroblasts. This model is suited to skin ageing and other long-term studies.

Gentiss also offers cell and tissue products, including primary human epidermal keratinocytes, ovine type I collagen, keratinocyte growth medium manufactured under GMP protocols, and ex vivo tissues and cultureware. Its testing services include cosmetic product testing, pharmaceutical testing, and product safety testing. Gentiss can provide product characterization to help support regulatory compliance and market access, and invites customers to request a quote or further information.