Famiglie GNAO1

Famiglie GNAO1 APS, also known as Smile for GNAO1, is an Italian nonprofit association founded in 2019 by families of children affected by neurodevelopmental disorders linked to mutations in the GNAO1 gene. The association aims to connect and support families, promote inclusion, raise awareness of this ultra-rare condition, and build collaboration among clinicians and researchers. GNAO1-related disorders can begin in early childhood and may involve epilepsy and movement difficulties; the association notes that no known treatment or cure is currently available.

Rather than offering commercial products, Famiglie GNAO1 provides information, community support, and opportunities to engage with the cause. Its website shares research and educational resources, news, and event information, including European conferences for families, clinicians, researchers, and rehabilitation professionals. The association also supports research through grant calls focused on GNAO1-related neurodevelopmental disorders. People can contribute through donations, volunteering, charitable gifts, and Italy’s 5×1000 tax allocation. By bringing families and professionals together, Famiglie GNAO1 works to advance understanding, research, and support for those affected.