GRADE is a global network of research centers dedicated to improving healthcare by promoting evidence-based decision-making. Present in multiple countries including Canada, China, Spain, and Australia, GRADE supports a collaborative approach to research and guidelines development. Each GRADE Center is led by expert directors who are committed to advancing the science of health interventions.

The network spans various regions, including the U.S. GRADE Network and specialized groups in Europe and Asia, facilitating knowledge sharing and best practices across borders. With centers located in prestigious institutions like McMaster University, Fudan University, and the American University of Beirut, GRADE focuses on enhancing the quality and effectiveness of health recommendations.

In addition to research initiatives, GRADE offers comprehensive resources and training opportunities to healthcare professionals, aiming to strengthen health systems worldwide. By fostering global collaboration, GRADE empowers stakeholders to implement sound clinical and public health decisions, ultimately leading to improved patient outcomes and healthcare quality.