Green Chemistry

GreenChemistry.ai is a green chemistry protocol optimization platform designed to help researchers identify practical ways to make laboratory procedures more sustainable. Users can paste a protocol, including synthesis steps, reagents, solvents, and conditions, or provide text extracted from a PDF or electronic lab notebook. The platform evaluates each step against the 12 Principles of Green Chemistry and presents an Impact Scoreboard with specific substitution recommendations.

Its recommendations draw on chemical and hazard information from PubChem, solvent data from CHEM21, and structure-based atom-economy calculations. Researchers can review and accept or reject proposed changes, then export a revised protocol. The service also provides before-and-after scorecards and confidence indicators; proposed changes require experimental validation.

GreenChemistry.ai describes its scoring as deterministic, auditable, and citable, with AI serving as the interface to cheminformatics tools including RDKit. For research and organizational use, the company offers enterprise access, custom integrations, electronic lab notebook connectors, DOZN export, and team dashboards for R&D teams and sustainability officers. It also provides a protocol analysis service through its website.