Located in the historic East Walnut Hills shopping district, the gallery showcases more than 150 artists in a 2,000-square-foot space. Local and regional creators are its primary focus, alongside artists from across the United States. Their work combines traditional techniques with contemporary design, celebrating the distinctive character of objects made by hand.

The collection spans pottery and ceramics, jewelry, metalwork, hot-worked and stained glass, woodcraft, art tiles, mosaics, fiber arts, prints, painting, paper, and garden art. Visitors can shop in person seven days a week, explore featured works and updates online or through social media, and arrange curbside pickup or shipping if they cannot visit. Indigenous also hosts artful events and shares artist news through its newsletters. Gift certificates are available in any amount, do not expire, and can be gift-packaged and mailed directly to recipients.