MESA is an initiative focused on sharing knowledge and catalyzing research towards a malaria-free world. Its work supports alignment between malaria research agendas and the priorities of countries where malaria is endemic, helping researchers, institutions and other stakeholders discover and connect with relevant research activity.

A central offering is MESA Track, a living database designed to provide updated information on malaria projects and the research portfolios of countries and institutions. Users can explore projects and thematic deep dives, and can submit a malaria project for inclusion. MESA also maintains a Resource Hub, a growing archive of useful malaria resources and tools, including reports, guidance and multimedia content.

The platform shares updates on malaria-related science and publishes information about grants, events and other opportunities. Its Correspondents Program reports from malaria events and conferences, with reports available to readers and opportunities to apply as a correspondent. MESA further offers a newsletter featuring monthly updates.