The Ministry of Environment, Science, Technology, and Innovation (MESTI) in Ghana is dedicated to fostering sustainable development through scientific research and technological advancement. Established to manage and regulate the nation's environmental needs, MESTI collaborates with various agencies, including the Council for Scientific and Industrial Research (CSIR) and the Environmental Protection Agency (EPA), to implement policies that ensure the protection of air, land, and water for future generations.

MESTI's projects focus on crucial areas such as coastal resilience, plastic waste reduction, and biosafety, exemplified by initiatives like the West African Coastal Area Resilience Investment Project II (WACA RESIP II). The Ministry also champions educational programs and professional training to empower women entrepreneurs, enhancing innovation within local communities. Through its various research and information systems, MESTI aims to promote a circular economy in Ghana, supporting a healthier environment through sustainable practices while actively engaging with stakeholders to address pressing environmental challenges.