Michalopoulos Lab is a computational biology and bioinformatics research group at the Biomedical Research Foundation of the Academy of Athens. Led by Ioannis Michalopoulos, the lab focuses on analysing biological data to investigate gene activity, genetic variation, and relationships between genes. Its work includes differential gene expression and co-expression analysis, using transcriptomic data from methods such as RNA sequencing and microarrays. The group also explores approaches to single-cell RNA sequencing data and gene network analysis.

The lab’s research spans a range of biomedical and biological topics, reflected in publications on Alzheimer’s disease, Long COVID, pharmacogenetics, immunogenetics, and gene expression in plants. Its work combines computational methods with data from clinical and experimental studies to identify patterns that may help explain biological processes and disease-related differences. The lab shares its publications, research updates, and web tools through its website. It also contributes to scientific discussion in its field, including editorial work on special issues devoted to differential gene expression and co-expression.