MS Living Well is an educational resource focused on helping people with multiple sclerosis make informed choices and maximize their ability to live well. Its content explains MS, diagnosis, MRI results, and what people may expect after diagnosis, with guidance for those newly diagnosed and their families. The site also covers treatment approaches, including disease-modifying therapies, interferons, glatiramer acetate, oral medications, and monoclonal antibodies, as well as symptom management and signs of worsening disease.

Alongside its educational materials, MS Living Well offers a blog and podcast featuring information and discussion about living with MS. The site connects visitors with the MS Center for Innovations in Care in St. Louis, including information about its clinicians, care team, treatment philosophy, and open clinical trials. It also highlights related services and facilities, such as outpatient therapy and wellness, imaging, and an MS infusion center. Personal stories from people living with MS illustrate varied experiences with treatment, work, family, fitness, and adapting to change. The resource provides contact details for the center in Missouri.