MyVariant.info is an innovative platform specializing in Variant Annotation as a Service. It offers streamlined REST web services designed for easy querying and retrieval of variant annotation data aggregated from numerous reputable data sources. The simplicity and performance of MyVariant.info make it an essential tool for researchers and developers looking to annotate variants or query known variants using specific criteria across multiple databases, such as CDK2 gene variants with a PolyPhen2 score over 0.99 found in the COSMIC database.

In addition to providing variant annotations, MyVariant.info supports powered applications that require variant data without the need for maintaining a local database. The project is backed by a team of experts from the Scripps Research Department of Integrative, Structural and Computational Biology, ensuring high-quality content and continuous improvements. Users can easily access the source code on GitHub, reflecting a commitment to transparency and community involvement. With its user-friendly approach, MyVariant.info stands as a valuable resource in the field of genomic research.