Nexus HealthSpan is a clinician-led preventive care brand based in Mission Viejo, California, focused on helping adults better understand their hormones, energy, metabolism, cardiovascular risk, and long-term health. Founded by Zachary Lott, MSN, ARNP, AGACNP-BC, the practice brings together symptoms, medical history, lifestyle, biomarkers, and risk factors rather than viewing routine bloodwork in isolation. Its comprehensive HealthSpan Assessment includes an in-depth consultation, clinically appropriate testing, thoughtful interpretation, and a personalized plan with clear priorities and ways to track progress.

Patients can choose online or in-person appointments, with consultations designed to allow time for questions and discussion. Nexus HealthSpan offers care pathways for arterial and cardiovascular health, heart attack and stroke prevention, cardiometabolic disease prevention, and carotid intima-media thickness (CIMT) ultrasound assessment. Hormone and metabolic services address men’s testosterone, energy, and erectile concerns, as well as women’s perimenopause, menopause, and related symptoms.

Hormone therapy options include bioidentical and menopausal hormone therapy and testosterone replacement, with evaluation and follow-up emphasized. The practice serves patients seeking earlier insight and informed, personalized preventive care