The Pediatric Epilepsy Surgery Alliance is an advocacy organization dedicated to improving the lives of children who may need neurosurgery for drug-resistant epilepsy. It helps families understand epilepsy surgery, explore evaluation options, and find information to support informed decisions. Its educational resources explain surgical procedures, including laser ablation, lesionectomy, lobectomy, hemispherectomy, corpus callosotomy, and neuromodulation treatments such as vagus nerve stimulation and responsive neurostimulation.

The Alliance also offers practical support for families navigating care before and after surgery. Programs include connections with Parent Support Navigators, financial aid for surgical evaluations, and help finding social services. Its resources address recovery, therapies, school and learning, caregiving, mental health, siblings, and the transition to adulthood. The organization provides free online courses and training for school teams, alongside information for healthcare professionals.

Through webinars, conferences, community events, research initiatives, and a patient registry, the Alliance brings families and professionals together. It also invites people to volunteer, fundraise, share their stories, and support its work to reduce delays in surgical evaluation.