Cannabis Strain Reference is a Canada-focused online resource that helps readers understand cannabis strains and product information in plain language. Its strain guides cover lineage, commonly reported effects, growing notes, and how to interpret figures on product labels, while distinguishing sourced lab results from unsupported marketing claims. The site notes that effects are not guaranteed and can vary by person, tolerance, and batch; lineage is identified as uncertain when it is not documented. Visitors can browse strains alphabetically or filter entries, and the site also publishes cannabis-related articles and reviews.

Alongside its reference content, the website presents an online shop with categories including cannabis flowers, budget buds, prerolls, and indica, sativa, and hybrid products. Its broader catalogue lists CBD oil, edibles, concentrates such as shatter, diamonds, and live resin, as well as hash, vape pens, and accessories. The site features named product lines and brands, including Kootenay Labs, Twisted Extracts, MOTA Infused, Firebars, Firechews, and Pineapple Express Kush Kitchen. It also provides navigation to contact information, reviews, and news.