PortalBio is an educational resource created by Y. V. Leontyeva, a top-category biology teacher with 15 years of teaching experience. Designed for students, teachers, and anyone interested in the life sciences, the portal provides biology lessons, study materials, and practical teaching resources for grades 5 through 11, including content for exam preparation. Its extensive subject areas cover botany, zoology, human anatomy, general biology, medicine, medicinal plants, flowers, gardening, and related topics. Visitors can also explore a glossary, tests, videos, presentations, and other useful information.

A central offering is ready-to-use lesson packages aligned with school curricula and the Federal State Educational Standards. Materials include lesson plans, worksheets, presentations, practical-work instructions, activities, and assessment resources. Recent examples address scientific methods and measurement, cell chemistry, and the study of algae, with hands-on tasks that help students investigate biological concepts. PortalBio presents biology as an engaging, practical subject and aims to save teachers preparation time while supporting structured learning. The site also offers a chat, newsletter subscription, reader reviews, and donation and contact information.