The Sarpong Group is a synthetic organic chemistry research laboratory at the University of California, Berkeley, led by Richmond Sarpong. Its work explores organic chemistry through total synthesis and methods development, using natural products as inspiration and as a platform for addressing longstanding challenges in chemical synthesis. The group develops novel strategies for constructing complex molecular targets and creates new methods that enable chemists to put those strategies into practice.

A particular focus is finding ways to build and cleave carbon–carbon bonds through skeletal rearrangements, including approaches that edit or reorganize molecular frameworks. Research spans the synthesis of natural products and the development of transformations with potential relevance to medicinal and pharmaceutical chemistry. The group shares its findings through peer-reviewed publications, research overviews, mechanisms, presentations, and other educational resources.

Its website also provides information about group members, values, fellowships, standard operating procedures, and events, alongside news of recent research and collaborations with academic and industry partners