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Explore therapeutic ultrasound for non-invasive, targeted genetic medicine delivery that improves precision and biodistribution. Learn more.
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SonoThera is a biotechnology company based in South San Francisco, California, developing genetic medicines for patients with serious diseases. Its approach uses therapeutic ultrasound to deliver genetic material without viral vectors. The company’s proprietary RIPPLE platform is designed to direct delivery to selected organs and tissues, support a range of DNA and RNA payloads without size restrictions, and allow repeat dosing. SonoThera aims to improve precision and biodistribution while developing treatments intended to be safe, well tolerated, and cost-effective.
Its research and development programs include potential genetic medicines for Duchenne muscular dystrophy, hemophilia A, and X-linked Alport syndrome. The company has reported preclinical work involving full-length dystrophin delivery to muscle tissues and ultrasound-mediated delivery of genetic material for other disease models. SonoThera is advancing these programs toward clinical development, with a first clinical trial for a Duchenne gene therapy targeted for 2027, according to its newsroom. The company also shares scientific findings, research publications, and program updates with patients, investors, and the biotechnology community.
The SonoThera name, logos and brand assets are trademarks of SonoThera and its affiliates. Brandfetch isn't affiliated with or endorsed by SonoThera. Their use is subject to SonoThera's brand guidelines.