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The RNA (epi)genetics laboratory of Dr Alper Akay at the University of East Anglia, Norwich. We study snRNA modifications, mRNA splicing, and the regulation of gene expression by dietary metabolites.
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#FFC20A
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255, 194, 10
45, 100, 52
0, 24, 96, 0
#141414
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20, 20, 20
0, 0, 8
0, 0, 0, 92
#DCA65A
Di Serria
220, 166, 90
35, 65, 61
0, 25, 59, 14
The Akay Lab is the RNA (epi)genetics laboratory led by Dr Alper Akay at the University of East Anglia in Norwich, United Kingdom. Established in 2020, the lab investigates how chemical modifications to small nuclear RNA (snRNA) influence messenger RNA (mRNA) splicing and gene expression, and how dietary metabolites affect these processes. Its research asks what snRNA modifications do, how they help determine RNA-splicing pathways, and how nutrient availability influences the methylation system.
The team combines genetics, mass spectrometry and nanopore sequencing, studying nematodes, including C. elegans, alongside E. coli bacteria, yeast and cultured human cells.
The lab shares open-access research papers and data, and emphasizes robust, reproducible science, honesty, respect and collaboration. It welcomes researchers and students of all genders and nationalities, including people who need extra support to pursue their scientific interests. While no funded PhD positions are currently available, students with external funding may apply.
The laboratory’s work receives support from UKRI, BBSRC, the Medical Research Council and the Big C Cancer Charity
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Science and Education
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