BioGRID is a biomedical research resource that provides an online repository of protein, genetic, and chemical interaction data. Its records are compiled through comprehensive curation of scientific publications and cover a broad range of model organisms, including humans, plants, animals, microbes, and viruses. The database also includes post-translational modification information, helping researchers explore molecular relationships and biological processes.

Users can search BioGRID by protein or gene, publication, or chemical, and filter results by organism. The site makes its data freely available through a searchable index, downloadable files in standardized formats, and a web service. Its curated collection is updated regularly, with new data added through monthly curation updates.

Related offerings extend BioGRID’s research support. BioGRID ORCS is a searchable repository of genome-wide CRISPR screens, with structured experimental metadata and downloadable data. Themed curation projects bring together interactions and publications focused on disease-relevant biological processes, while Gene Info eXtension (GIX), a browser extension, provides gene-product information from webpages. Together, these resources help researchers access and investigate diverse biomedical datasets.