The National Resource for Network Biology (NRNB) is dedicated to enhancing the field of biological networks through advanced analytics, visualizations, databases, and computational resources. Focusing on the complex interactions within gene, protein, and drug networks, as well as cell communication and social networks, NRNB offers essential tools for biomedical researchers. By utilizing the widely adopted Cytoscape Cyberinfrastructure, NRNB provides extensive support through tutorials, workshops, and a 24/7 help desk. The organization is committed to the development of open-source software technologies that facilitate network-based visualization and analysis, fostering biomedical discoveries.

NRNB is actively engaged in various research projects and collaborations to implement its tools in biomedical research. Notable initiatives include the Network Extracted Ontology (NeXO), which constructs comprehensive gene ontologies, and a method for network-based stratification of cancer mutations, enhancing patient cohort analysis. The Cytoscape App Store further enriches the user experience by allowing researchers to discover and promote relevant applications, bolstering the research community’s access to networking resources.