TrueCourse Biosciences is a scientific services company supporting biologics research and development, from early discovery through decisions that inform clinical advancement. Formed by bringing together NanoImaging Services’ cryo-electron microscopy expertise and Proteos’ protein production capabilities, the company offers integrated workflows to help researchers investigate complex biological systems and therapeutic candidates.

Its services include recombinant protein expression in insect, E. coli, and mammalian cells; protein purification; and custom antibody production. Structural biology offerings include high-resolution structure determination, cryo-EM, crystallography, gene-to-structure workflows, and epitope mapping. Researchers can also assess binding, affinity, and stability through biophysical characterization, including SPR, BLI, and DSF.

TrueCourse characterizes nanoparticles and delivery systems by examining particle morphology, size, shape, integrity, aggregation, payload encapsulation and distribution, and stability. Its work spans vaccines, gene and RNA therapeutics, and drug-delivery platforms, including lipid-based, polymeric, inorganic, and protein-based nanoparticles, as well as extracellular vesicles and bacteriophages. The company also supports workflows for validating AI-designed candidates and provides scientific resources such as publications, technical notes, webinars, and white papers.