True Health Ledger is a Boston-based educational formulary project focused on how medicines are studied, labeled, and used. Its site presents twelve medicine entries alongside twelve evidence files, covering antiparasitic, antibiotic, diabetes, nerve-pain, steroid, retinoid, hair-loss, antidepressant, and PDE5 inhibitor treatments. Each entry pairs a labeled dose or option with relevant clinical evidence and practical safety considerations, such as weight bands, kidney function, pregnancy precautions, resistance patterns, food effects, and drug interactions.

The project’s study files examine topics including clinical trials, treatment outcomes, resistance maps, dosing and tapering, and medicine development. Each file has a named reviewer, with contributors identified as physicians in internal medicine, infectious disease, and urology, and a pharmacist specializing in clinical pharmacology and drug safety. True Health Ledger describes its process as checking entries against current US FDA labels and having reviewers assess the material. The site is intended for reading and discussion, not for ordering or dispensing medicines; it states that nothing is sold and provides no checkout service.