TwinsUK is a prominent brand known for being the UK's largest adult twin registry and the most clinically detailed in the world. Established in 1992 by Professor Tim Spector from King's College London, the registry initially focused on investigating the incidence of osteoporosis and rheumatologic diseases in identical twins. Over the years, TwinsUK expanded its research scope and now boasts over 15,000 identical and non-identical twins from across the UK, aged between eighteen and one hundred.

Being one of the most extensively characterized adult twin cohorts globally, TwinsUK serves as an invaluable resource for scientists studying health and aging longitudinally. Their extensive dataset includes billions of data points, including questionnaires, clinical visits, genetic and omic data, and repeat measures over multiple timepoints. TwinsUK actively collaborates with external researchers and has shared over 250,000 samples and generated over 800 publications since 2012.

In addition to their scientific pursuits, TwinsUK is continuously working to enhance their resource by linking twins' official health, education, and environmental records for further research. Overall, TwinsUK plays a crucial role in advancing our understanding of various diseases and conditions through their comprehensive twin cohort