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Primary hyperoxaluria, or PH, is a family of rare genetic disorders causing hepatic oxalate overproduction that can result in progressive kidney damage and failure. Learn more about PH today.
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Uncovering PH is a Novo Nordisk educational website for US healthcare professionals focused on primary hyperoxaluria (PH), a family of rare genetic disorders that cause the liver to produce excess oxalate. The condition can lead to kidney stones, progressive kidney damage, kidney failure, and, in advanced cases, serious systemic disease. The site helps clinicians recognize possible warning signs, investigate genetic causes of kidney stones, and understand the mechanisms, diagnosis, and management of PH types 1, 2, and 3.
Its educational resources explain how liver enzyme deficiencies contribute to oxalate buildup and highlight the role of gene-specific analysis in reaching an accurate diagnosis. Visitors can access information about the burden of PH, including stone-removal procedures and potential treatment needs such as dialysis or combined liver-kidney transplantation in advanced cases. The website offers articles, a video, diagnostic guidance, and tools and resources for healthcare professionals.
It also provides references to published research supporting its educational content
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